How IDiots Would Activate the GULOP Pseudogene

The enzyme L-glucono-γ-lactone oxidase is required for the synthesis of vitamin C. Humans cannot make this enzyme because the gene for this enzyme is defective [see Human GULOP Pseudogene]. The GenBank entry for this pseudogene is GeneID=2989. GULOP is located on chromosome 8 at p21.1 in a region that is rich in genes.

Here's a diagram that compares what is left of the human GULOP pseudogene with the functional gene in the rat genome.

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