Oct. 28-30: Reserve These Dates!

 

THE GAIRDNER FOUNDATION 50TH
ANNIVERSARY TORONTO SYMPOSIUM:

Wednesday, October 28- Friday, October 30, 2009

WEDNESDAY, OCTOBER 28, 2009

Gairdner 50^th Anniversary Symposium on Stem Cells, Disease Mechanisms and Future Therapies in collaboration with the McEwen Centre for Regenerative Medicine.

Location: Macleod Auditorium, University of Toronto

Time: 9am -12:45pm

Co-Chairs: Dr. Janet Rossant, Sick Kids Hospital, Toronto, ON
Dr. Gordon Keller,Director, McEwen Centre for Regenerative Medicine, UHN, Toronto

Introduction: Dr. John Dirks, President and Scientific Director,
the Gairdner Foundation

9.00-9:30
Shinya Yamanaka, Professor, Department of Stem
Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Japan

Induction of pluripotency by defined factors

9.30-10:00
Gordon Keller, Director, McEwen Centre for Regenerative Medicine, Toronto, ON.

Directed differentiation of pluripotent stem cells to functional tissues

10.00-10:30
Andras Nagy, Senior Investigator Samuel Lunenfeld Research Institute, and Canada Research Chair in Stem Cells and Regeneration ,Toronto, ON

Transposon-mediated reprogramming provides a powerful exploratory tool for understanding stem cell induction

10.30-10:45 Break

10.45-11:15
Mario Cappechi, Distinguished Professor of Human Genetics and Biology, University of Utah School of Medicine, Salt Lake City, Utah

Stem cells of the intestine

11.15-11:45
Phillip Sharp,Institute Professor, Massachusetts Institute of Technology, Boston MA

The roles of small RNAs in stem cells

11.45-12:15
Samuel Weiss, University of Calgary, AB

Adult neurogenesis and the formation of social memories

12.15-12:45
Oliver Smithies, Excellence Professor of Pathology and Laboratory Medicine, University of North Caroline, Chapel Hill, NC

On being a scientist for 60 years

12.45 Reception

1:15-4:45 - Gairdner Global Health Symposium

Location: Dalla Lana School of Public Health, University of Toronto, 155 College Street, 6^th Floor, Toronto, ON M5T 3M7 Canada,

1:15-1:25

Introduction: Dr. John Dirks, President & Scientific Director, The Gairdner Foundation

Welcome: Dr. Jack Mandel, Director, Dalla Lana School of Public Health, University of Toronto

The Global Health Stage

Chair: Kiyoshi Kurokawa, Professor, National Graduate Institute for Policy Studies, Tokyo

1:25-1:40
Jeff Koplan, Director of Global Health, Emory University

What's global health and why is it important?

1: 40-1:55
Tachi Yamada, President of Global Health Program, Gates Foundation

Innovation and access in global health

1:55-2:10Mark Walport,Director, Wellcome Trust.
Building capacity

2:10-2:25
Peter Singer, Director, McLaughlin-Rotman Centre
for Global Health, University Health Network and University of Toronto

Global health: why Canada should care and what Canada should
do.

2:25-2:45
Discussion

2:45-3:00 Break

The Challenge of Chronic
Disease

Chair:Alan Bernstein, Executive Director, Global HIV Vaccine Enterprise

3:00-3:20
Nubia Munoz, Inaugural Canada Gairdner Global Health award recipient

Burden of cancer associated with infectious agents in developing countries.

3:20-3:35
John Sulston, Cambridge, UK
What is Science for anyway?

3:35 -3:50
Margaret G. McGlynn, President, Merck Vaccines, Merck and Company Inc.
The evolving global vaccine landscape

3:50-4:05 Prabhat Jha, Director, Centre for Global Health Research, University of Toronto
Death and tobacco taxes

4:05-4:20
Richard Peto,Professor of Medical Statistics and Epidemiology, Co-Director, CTSU, Oxford University
Halving adult mortality worldwide

4:20-4:40 Discussion

4:40-4:45 Conclusion

Dr. John Dirks, President and Scientific Director, the Gairdner Foundation

1:30-4:45 -The Cell: An Endless Frontier

Location: Macleod auditorium,
University of Toronto

1:30-1:40 Introduction

1:40-2:00pm
Elizabeth Blackburn, Morris Herzstein Endowed Professor in Biology & Physiology, Department of Biochemistry & Biophysics University of California, San Francisco
How cells - and organisms - respond to perturbing their telomere maintenance

2:00-2:20pm
Ulrich Hartl, Max- Planck Institute for Biochemistry, Martinsried, Germany

The cellular machinery of protein folding: Molecular chaperones in health and disease

2:20-2:40
Avram Hershko, Technion Institute of Technology, Haifa

Roles of ubiquitin-mediated protein degradation in cellular regulation

2:40-2:55 Coffee Break

2:55-3:15pm
Bob Horvitz, David H. Koch Professor of Biology, Massachusetts Institute of Technology, Boston and Investigator, Howard Hughes Medical Institute

Genetic control of programmed cell death in C. elegans

3:15-3:35pm
Victor Ambros,Professor, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA

Small RNAs in every corner of the cell

3:35- 3:55
Gary Ruvkun,Professor of Genetics, Harvard Medical School

A C. elegans endocrine system that couples detection of xenobiotic drugs to regulation of reproduction and longevity

3:55 - 4:15
Robert G. Roeder, Arnold and Mabel Beckman
Professor, Laboratory of Biochemistry and Molecular Biology, Rockefeller University, NY

Transcriptional regulatory mechanisms in animal cells

4:15- 4:35pm Richard Axel, Investigator, Howard Hughes Medical Institute and University Professor, Columbia University, NY
Topic TBA

4:35pm Concluding Remarks

THURSDAY, OCTOBER 29, 2009

7:15 - 9:00am -
Gairdner Industry Breakfast, Unclogging the Pipeline: Rejuvenating drug discovery
Location: MaRS Centre, MaRS Collaboration Centre Auditorium


Moderator:Cal Stiller, Chair, Genome Canada/Bioquest Innovations Inc. /Ontario Institute for Cancer Research and Professor Emeritus, University of Western Ontario; Toronto, ON


Speakers:
Philip Sharp, Institute Professor, Massachusetts Institute of Technology; Cambridge, MA

Corey Goodman, Past President, Biotherapeutics and Bioinnovation Center, Pfizer Inc.; San Francisco, CA
David Baltimore, President Emeritus, Robert Andrews Millikan Professor of Biology, California Institute of Technology; Pasadena, CA

Please RSVP by email tothegairdner@gairdner.org, include the first and last name of the total number of guests attending.

9:00 - 3:00 -2009 Canada Gairdner Recipients' Lectures, The Charles Hollenberg Symposium

Location: JJR Macleod auditorium, University of Toronto

9:00am Dr John Dirks, Welcoming remarks

9:15 -9:45am Dr. Peter Walter, Professor, Department of Biochemistry, University of California, San Francisco Investigator of the Howard Hughes Medical Institute, CA,
Protein homeostasis in health and
disease

9:45-10:15am Dr. Kazutoshi Mori, Professor, Department of Biophysics, Graduate School of Science, Kyoto University, Japan
The unfolded protein response: To
mammals and beyond

10:15-10:30 Coffee Break

10:30-11:00am Dr. Lucy Shapiro, Director, Beckman Center for Molecular and Genetic Medicine,Professor, Developmental Biology, Stanford University School of Medicine, Stanford, CA
The systems architecture of the bacterial cell cycle

11:00-11:30am Dr. Richard Losick, Professor, Microbial Development and Gene Regulation, Harvard University, Cambridge, MA
Developmental biology of a simple organism

11:30-12:00pm Dr. David Sackett, Professor Emeritus, Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, ON
On the tribulations of not performing
randomized trials

12:00-1:00pm Lunch Break

1:00-1:05 John Dirks, Introduction of the Inaugural Canada Gairdner Global Health Award

1:05-1:45 Dr. Nubia Munoz, Emeritus Professor, National Cancer Institute, Bogota, Colombia and Visiting Scientist, Catalan Institute of Oncology, Barcelona
From causality to prevention: the case of cervical cancer

1:45-2:15 Dr. Shinya Yamanka, Professor, Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Japan
Induction of pluripotency by defined factors

2:15- 2:45 Dr. Sydney Brenner, Distinguished Professor, The Salk Institute, San Diego
Humanity's genes

FRIDAY OCTOBER 30, 2009

8:45-3:00-Gairdner/Nobel and Gairdner Laureate Forums

Location: Convocation Hall, University of Toronto
All sessions will present a moderated panel discussion,
followed by Q&A from the audience.

Friday's events are free but registration is required.
Click here.

8:45-10:15amAttack and Repulsions: Infections and the Immune System

Dr. David Baltimore (Moderator), Robert Andrews Millikan Professor of Biology, California Institute of Technology, CA

Dr. Ralph Steinman, Henry G. Kunkel Professor & Sr. Physician, The Rockefeller University, New York

Dr. Emil Unanue, Paul & Ellen Lacy Professor, Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO

Dr. Rolf Zinkernagel, University of Zurich, Zurich, Switzerland


10:30-12:00pm The Metabolome: Food and Fuel for Thought

Dr. Joe Goldstein (Moderator), Julie and Louis A. Beecherl Distinguished Chair in Biomedical Science, Southwestern Medical Center, University of Dallas, TX

Dr. Jeff Friedman, Marilyn M. Simpson Professor, The Rockefeller University, New York

Dr. Tony Pawson, University Professor, Program in Molecular Biology &Cancer, Samuel Lunenfeld Research Institute, Toronto

Dr. Michael Brown, Paul J. Thomas Chair in Medicine, Southwestern Medical Center, University of Texas, Dallas, TX

Dr. Ron Evans, Professor, Salk Institute for Biological Studies, La Jolla California

2:00-3:30pm Cancer: Can New Insights into Biology Yield Better Results?

Dr. Michael Bishop (Moderator) Chancellor, University of California, San Francisco

Dr.Harald zur Hausen, Professor Emeritus, German Cancer Research institute, Heidelberg, Germany

Dr.Dennis Slamon, Chief, Department of Hematology, Oncology, University of California, Los Angeles

Dr. Bob Weinberg, Professor of Biology, Member, Whitehead Institute, MIT, Cambridge, MA

Dr. Barry Marshall, International Research Foundation for Helicobacter and
Intestinal Immunology, Virginia

7:00- 8:30pm
The Personalized Genome: Do I Want to Know?

Dr. Michael Hayden, Director and Senior Scientist, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver

Dr. Sydney Brenner, Distinguished Professor, The Salk Institute, San Diego

Charles Sabine, Award winning NBC News correspondent and carrier of the gene for Huntington's Disease

If you need more information please contact Sheila Robinson at

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